Diosgenin ppt

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Second, diosgenin has certain prevention and cure function for osteoporosis in rats induced by retinoic acid. Our study provides a theoretical base for the further development of diosgenin. Diosgenin prevents bone loss on retinoic acid induced osteoporosis rats. Highlights: Diosgenin has preventive and therapeutic effect on osteoporosis. Sep 26, 2001 · Previously, we demonstrated that a plant steroid, diosgenin, was a new megakaryocytic differentiation inducer of human erythroleukemia cells . In this study, we investigated the effect of diosgenin on the proliferation rate, cell cycle distribution and apoptosis in the human osteosarcoma 1547 cell line. Diosgenin Catabolism. When cursor points to a box further details will be displayed in a tooltip window. If you click on the box it will change to the appropriate reaction scheme or enzyme specification. 2. Wild Yam Extractis reach in diosgenin, so it became the most popular source of natural progesterone. 3. Applied in pharmaceutical field, it is used in treating bladder weakness, diarrhea, dysentery, coughs, and thirst . 4. Applied in cosmetics field, it is one indispensible additive for cosmetic products. The sugar-free (aglycone), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Saponins of Dioscorea are used for washing silk, wool and hair, and as fish poison. Cortisone prepared from these species is used in rheumatic diseases and ophthalmic disorders. 2. Wild Yam Extractis reach in diosgenin, so it became the most popular source of natural progesterone. 3. Applied in pharmaceutical field, it is used in treating bladder weakness, diarrhea, dysentery, coughs, and thirst . 4. Applied in cosmetics field, it is one indispensible additive for cosmetic products. 3.1 Effects of diosgenin, solasodine, and tomatidine on the expression of FAS in HER2‐overexpressing breast cancer cells. Diosgenin, solasodine, and tomatidine (Fig. 1A) are naturally occurring plant steroids and have been shown to have anti‐neoplastic activities. To investigate the possible relationship between the chemical structure and ... PDF | Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata , Smilax China, and Trigonella foenum graecum . ... (PPT) []. 3.1.2. Analytic al Methods. Classical ... Diosgenin is a precursor of steroid hormones and is found in fenugreek (Trigonella foenum graecum), an annual herb belonging to the family Leguminosea. 16 Fenugreek is native to the eastern shores of the Mediterranean Sea, but is also grown in Asia, the Middle East, Europe and the United States. 17 It has repeatedly been shown to have potent ... Diosgenin is a triterpene and a glycone derivative of dioscin. Yams, Trigonella foenum-graecum and Costus speciosus are some of its source. Application Diosgenin has been: • used as a standard in the analysis of total saponins in Sapindus rarak Diosgenín: pôvod, popis a využitie. Diosgenín je látka prírodného charakteru získavaná z rastlín, pričom z chemického hľadiska ide o produkt hydrolýzy kyselín, silných báz a extraktov saponínov. Other articles where Diosgenin is discussed: sapogenin: …of converting the steroid sapogenin diosgenin into progesterone have been developed. An abundant source of diosgenin is a Mexican yam called cabeza de negro, and progesterone made from it is used in producing steroid hormones. Diosgenin, mainly produced by Dioscorea species, is a traditional precursor of most hormonal drugs in the pharmaceutical industry. The mechanisms that underlie the origin and evolution of diosgenin biosynthesis in plants remain unclear. Sep 26, 2001 · Previously, we demonstrated that a plant steroid, diosgenin, was a new megakaryocytic differentiation inducer of human erythroleukemia cells . In this study, we investigated the effect of diosgenin on the proliferation rate, cell cycle distribution and apoptosis in the human osteosarcoma 1547 cell line. The diosgenin quantification in leaves and rhizome samples of Costus speciosus, Costus pictus and Costus igneus was performed using HPLC analysis. All the samples showed characteristic peaks of diosgenin at the same retention time as that of standard diosgenin. The concentrations of diosgenin in different samples were Sep 26, 2001 · Previously, we demonstrated that a plant steroid, diosgenin, was a new megakaryocytic differentiation inducer of human erythroleukemia cells . In this study, we investigated the effect of diosgenin on the proliferation rate, cell cycle distribution and apoptosis in the human osteosarcoma 1547 cell line. Aug 09, 2014 · Dioscorea is a genus of flowering plants, and some Dioscorea species are known and used as a source for the steroidal sapogenin diosgenin. To screen potential resource from Dioscorea species and related medicinal plants for diosgenin extraction, a rapid method to compare the contents of diosgenin in various plants is crucial. An ultra-performance liquid chromatography (UPLC) coupled with diode ... concentration by heating diosgenin in a pressure reactor dissolving it in commercial grade of xylene containing low concentration of acetic anhydride (diosgenin: Ac 2 O:: 1mol:3.5mol) at a temperature of 200°C to react selectively on the pyran oxygen of diosgenin 3 with concomitant acetylation of 3β- hydroxyl group [24] [Figure 1]. Chart and Diagram Slides for PowerPoint - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Diosgenin purchased from MCE. Usage Cited in: Cell Physiol Biochem. 2016;39(4):1626-37. Arithmetic means ± SEM (n = 10) of erythrocyte annexin-V-binding following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Diosgenin (5-15 µM). Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. PDF | Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata , Smilax China, and Trigonella foenum graecum . ... (PPT) []. 3.1.2. Analytic al Methods. Classical ... In addition, 1% FSP or 0.1% diosgenin fed during the promotional stage caused a significant reduction ( P ≤ 0.001) of multicrypt foci compared with control. Dietary diosgenin at 0.1% and 0.05% inhibited total colonic ACF and multicrypt foci formation in a dose-dependent manner. The sugar-free (aglycone), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Saponins of Dioscorea are used for washing silk, wool and hair, and as fish poison. Cortisone prepared from these species is used in rheumatic diseases and ophthalmic disorders. Chart and Diagram Slides for PowerPoint - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. 1. Arch Biochem Biophys. 1961 Jan;92:13-6. Biosynthesis of diosgenin in Dioscorea tubers. HEFTMANN E, BENNETT RD, BONNER J. PMID: 13712748 [PubMed - indexed for MEDLINE] Diosgenin A 198-202 ! 282 ± 54 Diosgenin B ! 187-198 219 ± 68 acetate ; Diosgenin C 192.5-194 145 ± 20 acetate Diosgenin ; D 192-196 -121° 145 ± 20 acetate'' Diosgeuin E : 203.5-206 156 ± 15 Diosgenin F 203-205 -120° 137 ± 15 Diosgenin G 229-232 — benzoate Diosgenin H 207-208 141 ± 15 ° See text. 6 Kofler block, corrected. r In ... Aug 09, 2014 · Dioscorea is a genus of flowering plants, and some Dioscorea species are known and used as a source for the steroidal sapogenin diosgenin. To screen potential resource from Dioscorea species and related medicinal plants for diosgenin extraction, a rapid method to compare the contents of diosgenin in various plants is crucial. An ultra-performance liquid chromatography (UPLC) coupled with diode ... Diosgenin Catabolism. When cursor points to a box further details will be displayed in a tooltip window. If you click on the box it will change to the appropriate reaction scheme or enzyme specification. Diosgenin benefit and side effects, research review by Ray Sahelian, M.D. June 17 2015. Diosgenin is a steroidal saponin, which is extracted from the root of wild yam, known by its botanical name as Dioscorea. Other plant steroids include hecogenin and tigogenin. Chart and Diagram Slides for PowerPoint - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Jun 21, 2012 · Diosgenin: Diosgenin against Chemical Induced Mammary Carcinogenesis and In MCF-7 Human Breast Cancer Cell Line [Jayaraman, Jagadeesan, Kulanthaivel, Langeswaran, Subbaraj, Gowtham Kumar] on Amazon.com. *FREE* shipping on qualifying offers. Breast cancer is one of the second most common cancers in the world. Dioscin is a spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage. It has a role as a metabolite, an antifungal agent, an antiviral agent, an antineoplastic agent, an anti-inflammatory agent, a hepatoprotective agent, an apoptosis ... 26-Hydroxycholesterol-26-14C was converted by D. floribunda to diosgenin. This result suggests that oxygenation at C-26 may be the first step in the biosynthesis of diosgenin from cholesterol. No diosgenin was formed from kryptogenin-26-14C by D. composita, nor was diosgenin-26-14C converted to its C-25 epimer, yamogenin, by the latter plant. Other articles where Diosgenin is discussed: sapogenin: …of converting the steroid sapogenin diosgenin into progesterone have been developed. An abundant source of diosgenin is a Mexican yam called cabeza de negro, and progesterone made from it is used in producing steroid hormones.